A few follow on thoughts to “How To Build a Biotech Cluster That Isn’t Boston or SF”
I wanted to share some thoughts on “How To Build a Biotech Cluster That Isn’t Boston or SF,” many of them stemming from the #AtlasLSR tweets of November 9. I was reading them going, “yes!”
This tweet from Bruce kicked it off; ”Having your R&D rooted in a ‘science hub’ increases odds of Phase 2-3 success by 2-fold.“
Next, this via Katrine Bosley; “quality of scientific publications is one” correlate with R&D success.
To tie that back, Recruit Rock Star Scientists; theoretically, the PIs that have been recruited to UofL via Bucks for Brains are publishing in quality journals. I say theoretically because I haven’t tested that quantitatively. And, I have to say, there are PIs who have been at Louisville since before Bucks for Brains that publish in high impact factor journals, too (e.g. Jon Klein @JonBKlein).
Regarding drug development success rates and what does or does not correlate with success, I asked Katrine, “Do the people?“
The answer is, “yes.” So having access to people–with experience–is a good thing. Related, on the academic side, a good read is “Stranger in a strange land?” by Bassil Dahiyat in Nature Biotechnology. In it he notes, “if you are in academia and aspire to start a company, it really helps if you are at an institution where you are surrounded by peers and professors already experienced with the biotech industry.”
Michael Gilman helped kick off a discussion of “hub,” captured, in part, here via Appeering.
Of note, back to the point that being in a science hub correlates with success.
“Why so few hubs overall?” Clearly I think it has a lot to do with people, and hopefully this helps support that theory, but certainly there are other factors. And while I have some experience, I don’t have all the answers.
That’s why I try to listen (even if it’s via Twitter!) and learn from others with experience. And that may be the take home point of all of this. In many ways building a biotech cluster is like building any other startup; you have to do your due diligence and test your assumptions.
* Thanks again to Luke and Xconomy for the opportunity.





Relative to this original piece http://www.xconomy.com/national/2012/11/20/how-to-build-a-biotech-cluster-that-isnt-boston-or-sf/, see this by Bruce Booth- http://lifescivc.com/2012/12/the-entrepreneurial-diaspora-enabled-by-biotech-ma/
Also see Human Capital in Biotech: Recycle, Reuse, Reduce http://thenextelement.wordpress.com/2013/01/03/human-capital-in-biotech-recycle-reuse-reduce/ by Laura Strong.